??.z%R ?0?0?0?0 o? Op? T ???P??^ ???Pg?? "[Special lecture/Symposium]" "Representative phthalate pharmacokinetics in chimeric mice with humanized liver" "Hiroshi Yamazaki" "Green Plasticizer Development Forum 2016" Shanghai 2016/04/23^?2016/04/25 "[Poster presentation]" ?bf0?0K0?0???0?0?0?0?0?0?0?0?0n0?N?u? }??\??k0??Y0?0xvz ?(gi_?R0Qgq\xQu`0Igq\??7u0?\¦¡?O?N0q\]im?S0?^0u][?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" T?|^y?u???0?0?0?0?0?0?0L0?0_0?0Y0?0?0P4503Au? }h0n0??ir?v?N\O(u Qgq\xQu`0 P?g*Q??0?e?]?}P[0'YEN?OwBz0q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" ?e,g?Nk0J0Q0?0?0?0?0?0?0?0?0?0?\?un0N?Vh0j0?0?e???0?0?0?0+T g?0?0?0?0?0?0?0?0?03?0?0?0?0?0?0n0?g gr¦¡?}0n4lN}P[0?_q\[t?0?h7??}0!n???x0q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" ?e,g?Nk0J0Q0?0?0?0?0?0?0?0?0?0?\?un0?S?Vh0j0?0?e???0?0?0?0+T g?0?0?0?0?0?0?0?0?03z?OP[ Ypun0?g ?_q\[t?0n4lN}P[0gr¦¡?}0?h7??}0!n???x0q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" ?0?0??0}??y i?0?0?0J0?0s0?0?0?0?0?0?0utf[?v??ir?RKa?0?0?0?0;m(uW0_0?0?0?0?0?0P450?0?0?0?0?W?n0?0?0@?-N?o?^?c?y?N,n n4lN}P[0 N?N?n?HY0?l¦¡*geg0 N?Sck*Y?0?[¦¡?l?^0\????0?N N???S0PO0(gH0?0K00+g4l m?_0q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" "?e???0?0?0?0?0?0P450 2Ju? }n0 T?[J0?0s0_j???g" N?Sck*Y?0?\,gu}?P[0?[¦¡?l?^0?N N???S0PO0(gH0?0K00q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Oral presentation]" ?0?0?0?0?0?0??n0?0?0?0?0?0?0x?S?v?N?n0?zSOx??b'` ?l¦¡*geg0 N?Sck*Y?0?w?NU0O0?00?[¦¡?l?^0?N N???S0\????0PO0(gH0?0K00q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" ?0?0?0?0?0?0B0?0D0o0?0?0?0?0?0?0??0}??0(uD0_0??ir?f2?k0?0?0?0?0?0?0?0P450??\n0U??O 4?(g??P[0 N?Sck*Y?0Qgq\xQu`0?[¦¡?l?^0?w?\?RHYP[0\????0?N N???S0PO0(gH0?0K00q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" ?0?0?0?0?0?0J0?0s0?0?0?0?0?0?0\x?P450u? }k0?0?0?0?0?0?0?0x?S?v?N? N?Sck*Y?0P}?W?S??P[0?[¦¡?l?^0?N N???S0PO0(gH0?0K00q\]im?S ?e,g??f[O,{136t^O *j\m 2016/03/26^?2016/03/29 "[Poster presentation]" "An Association between Plasma and Urinary Levels of Trimethylamine-N-oxide(TMAO) and Metabolic Factors in a Population of Community-dwelling Japanese." "Ako Fukami, Hisashi Adachi, Mika Enomoto, Eita Kumagai, Sachiko Nakamura, Yume Nohara, Erika Nakao, Nagisa Morikawa, Tomoko Tsuru, Hiroshi Yamazaki, Kei Fukami, and Yoshihiro Fukumoto" ,{80?V?e,g?_?thVf[Of[S??O ?N?S 2016/03/18^?2016/03/20 "[Special lecture/Symposium]" ?0?0>e\?}?QÈe??f?}?U??On0?[??J0?0s0APDDn0?cHh `l0uOef_0Qgq\xQu`0q\]im?S S?-APDDT T?0?0?0?0?0?00 ??0?0RIf??n0?[?ec? ? qg?N 2016/03/14 "[Special lecture/Symposium]" "??ir?N?u? }n0Y?Wh0?N?irk0l?e?]?0uZ0?0?S??'`-?e,g?Nk0J0Q0?0?0?0RIf??n0???'`- " q\]im?S S?-APDDT T?0?0?0?0?0?00 ??0?0RIf??n0?[?ec? ? qg?N 2016/03/14 "[Poster presentation]" "In Vivo Model for Predicting Organophosphate Toxicity using Humanized-Liver TK-NOG Mouse" "Hiroshi Suemizu, Miyuki Kuronuma, Kenji Kawai, Norie Murayama, Masato Nakamura and Hiroshi Yamazaki" "The Society of Toxicology 55th Annual Meeting" "New Orleans, USA" 2016/03/13^?2016/03/17 "[Oral presentation]" "?0?0?0?0?N?u? }?0?0?0?0?0 P450 2A6 ¦¡u?WJ0?0s0hQ k d?Wz?OP[$R?[?ln0?k?" ?\,gD0Z000n4lN}P[0?h7??}0q\]im?S ,{70?VV??0?0?0?0?0;S?y'Yf[;Sf[Of[S??O ?]] 2016/03/12 "[Special lecture/Symposium]" "Metabolic Activation of Xenobiotics by Polymorphic Drug-metabolizing Enzymes" "Hiroshi Yamazaki" "The 13th Asia Pacific Federation of Pharmacologist Meeting (APFP)" Thailand 2016/02/01^?2016/02/03 "[Special lecture/Symposium]" ?0?0??ir?RKa?N,n?0?vcW0_0?0?00?0?0?0?0?0?0h0?0?0??0}??y i?0?0?0n0;m(uxvz q\]im?S ",{38 ?V ??ir?RKa?q?Ot^O" \m~g 2015/11/30^?2015/12/01 "[Poster presentation]" "N?_j?????[Bfk0J0Q0?0??ir???v?N\O(un0?N,n?DPP-4;??[?? ?0?0?0?0?0?Oh0W0f0" n4l?y?O0?N8N?U?U0q\]im?S0ENs|?OL? ,{25?V?e,g;SBv??f[Ot^O *j\m 2015/11/21^?2015/11/23 "[Special lecture/Symposium]" "Comparison of drug oxidations in humans, primates, and rodents" "Hiroshi Yamazaki" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Special lecture/Symposium]" "Flavin-containing monooxygenase 3: Individual differences and drug interactions" "Makiko Shimizu and Hiroshi Yamazaki" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Poster presentation]" "Functional polymer-dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes" "Yuichiro Higuchi, Kenji Kawai, Tatsuro Kanaki, Hiroshi Yamazaki, Chesne Cristophe, Guguen-Guillouzo Christiane, Hiroshi Suemizu" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Poster presentation]" "Pharmacokinetics of efavirenz after oral and intravenous administration of efavirenz to genotypedcynomolgus monkeys" "Yusuke Kitsugi, Kanami Ikeda, Atsushi Matsuoka, Takaaki Tokunaga, Natsumi Tomida, Haruka Shirosawa, Takahiro Yoshikawa, Yasuhiro Uno, Kazuhide Iwasaki, Masahiro Utoh, Hiroshi Yamazaki, Shinya Hosaka" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Poster presentation]" "Comparison of catalytic properties in cytochrome P450 3A4 and 3A5 for various compounds including0endogenous steroid hormones by molecular docking simulation" "Toshiro Niwa, Norie Murayama, Yurie Imagawa, Hiroshi Yamazaki" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Poster presentation]" "Time-dependent inhibition of OATP-mediated transport by cyclosporine A is reproduced in cynomolgus monkeys" "Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Yasuhiro Uno, Hiroshi Yamazaki, Toshiyuki Kume" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Poster presentation]" "Induction of drug metabolizing enzymes by thalidomide dependent on pregnane X receptor (PXR) in human livers as evident using PXR-knockout HepaRG cells" "Norie Murayama, Kanako Yajima, and Hiroshi Yamazaki" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Poster presentation]" "Analysis of cytochrome P450 regulators in cynomolgus macaque" "Yasuhiro Uno and Hiroshi Yamazaki" "30th JSSX Annual Meeting" qg?N 2015/11/12^?2015/11/14 "[Poster presentation]" "Cytochrome P450-dependent warfarin and caffeine metabolism in marmosets, monkeys, and humans" "Hiroshi Yamazaki, Shotaro Uehara, Yasuhiro Uno, and Erika Sasaki" "20th North American ISSX Meeting" "Orlando, USA" 2015/10/18^?2015/10/22 "[Poster presentation]" ?0?0?0?0?0?0??n0?0?0?0?0?0?0?N?n0?g ?l¦¡*geg0 N?Sck*Y?0?[¦¡?l?^0\????0PO0(gH0?0K00q\]im?S ,{59?V?e,g??f[O??qg/e?'YO qg?N 2015/09/12 "[Poster presentation]" ?0?0?0?0?0?0??n0?0?0?0?0?0?N?L}?n0?g 4?(g??P[0 N?Sck*Y?0?[¦¡?l?^0\????0PO0(gH0?0K00q\]im?S ,{59?V?e,g??f[O??qg/e?'YO qg?N 2015/09/12 "[Special lecture/Symposium]" "Human Drug Metabolism by Cytochrome P450 Enzymes" "Hiroshi Yamazaki" "2nd Symposium of SPU Innovative Project for Pharmaceutical Analyses of Covalent Modification in Biomolecules" qg?N 2015/09/01 "[Special lecture/Symposium]" ?0?0?0?0?0?0k0J0Q0?0?0?0?0?0?0P450h0?0?0?0?0?0x???yu? }n0?g ?[¦¡?l?^0q\]im?S ,{42?V?e,g?k'`f[Of[S??O §×?l 2015/06/29^?2015/07/01 "[Special lecture/Symposium]" ?[??RirJ0?0s0?0?0n0??irx?Su? };m'`n0?k? q\]im?S0?[¦¡?l?^ ,{42?V?e,g?k'`f[Of[S??O §×?l 2015/06/29^?2015/07/01 "[Oral presentation]" ?e,g?Nn0?0?0?0?0?0?0?0?0?\?uk0??Y0?0'Y??!j???g CSI?^c[P[0n4lN}P[0gr¦¡?}0 N??0P[0?S0u?l_N?R0q\]im?S ,{69?VV??0?0?0?0?0;S?y'Yf[;Sf[Of[S??O ?]] 2015/06/27 "[Oral presentation]" @??m??g?`?k0J0Q0?0FMD$Ph0trimethylamine-N-oxide0?_@??{?u Yh0n0i? ?7?IQ?^0 N?Q?N ^P[0?_?SP[0fk0u?? g?0?[-NEN?N0?h?QGRP[0q\?h?n?[?0?O?_4X}P[0?o?w1u?0 N0u?_P[0'Y??ckN?0n4lN}P[0q\]im?S ,{60?V?e,g??g;Sf[Of[S??O *j\m 2015/06/26^?2016/06/28 "[Poster presentation]" S_?0?0?0?0?0k0J0Q0?0Z???uP?n0N?O?0L}?W0f0 ?h?QGRP[0?7?IQ?^0?o?w1u?0?O?_4X}P[0q\?h?n?[?0?[-NEN?N0fk0u?? g?0?_?SP[0 N?Q?N ^P[0 N0u?_P[0'Y??ckN?0n4lN}0q\]im?S ,{60?V?e,g??g;Sf[Of[S??O *j\m 2015/06/26^?2016/06/28 "[Poster presentation]" "Comprehensive evaluation for substrate selectivity of cynomolgus monkey cytochrome P450 2C enzymes" "Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno, Hiroshi Yamazaki" "19th International Conference on Cytochrome P450" qg?N 2015/06/12^?2015/06/15 "[Poster presentation]" "Human cytochromes P450-mediated regioselective hydroxylation of steroid hormones" "Toshiro Niwa, Norie Murayama, Yurie Imagawa, and Hiroshi Yamazaki" "19th International Conference on Cytochrome P450" qg?N 2015/06/12^?2015/06/15 "[Poster presentation]" "Identification and analysis of CYP2B6 variants in cynomolgus and rhesus macaques" "Yasuhiro Uno, Shotaro Uehara, and Hiroshi Yamazaki" "19th International Conference on Cytochrome P450" qg?N 2015/06/12^?2015/06/15 "[Poster presentation]" "Molecular cloning, expression and functional characterization of marmoset cytochrome P450 2A6 " "Shotaro Uehara, Yasuhiro Uno, Norie Murayama, Makiko Shimizu, Hiroshi Yamazaki" "19th International Conference on Cytochrome P450" qg?N 2015/06/12^?2015/06/15 "[Poster presentation]" "Mutations of flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria" "Makiko Shimizu and Hiroshi Yamazaki" "19th International Conference on Cytochrome P450" qg?N 2015/06/12^?2015/06/15 "[Poster presentation]" "The modulation of physiological condition for expression of P450s in differential cryopreserved HepaRG cells" "Norie Murayama, Kanako Yajima, Hiroshi Yamazaki" "19th International Conference on Cytochrome P450" qg?N 2015/06/12^?2015/06/15 "[Poster presentation]" "In Vivo R/S-Warfarin Metabolism Mediated by Polymorphic P450 2C19 in Cynomolgus Monkeys" "Masahiro Utoh, Takahiro Yoshikawa, Makiko Shimizu, Kazuhide Iwasaki, Yasuhiro Uno, Hiroshi Yamazaki" "19th International Conference on Cytochrome P450" qg?N 2015/06/12^?2015/06/15 "[Special lecture/Symposium]" Y?Wh0??T???n0SO?Q?RKa q\]im?S "?e,g??T??yf[O ,{62 ?Vf[S??O" ^y8b 2015/05/28^?2015/05/30 "[Poster presentation]" "??ir?N??Wcytochrome P450?Ss0?0?0?0?0?0?N?u? }k0?0?0?0?0?0?0?0?N?" 9N??Og0Qgq\xQu`0?N?]?S?u`0q\]im?S ?e,g??dRf[O,{30t^O w?] 2015/05/21^?2015/05/23 "[Poster presentation]" "Cytochrome P450 (CYP0P450) 3A4?Ss0CYP3A5?0+T?0?0?0?N??WP450k0?[Y0?0T.z?bw???n0?v?N\O(u" ?N?]?S?u`0Qgq\xQu`0q\]im?S09N??Og ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Poster presentation]" "Cytochrome P450 (CYP0P450) 3A4?Ss0CYP3A5?0+T?0T.z?0?0P450k0?0?0?0?0?0?0?0?N?" 9N??Og0Qgq\xQu`0?N?]?S?u`0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Poster presentation]" "?0?0?0?0?0?0utf[?v??ir?RKa?0?0?0?0;m(uW0_0?0?0?0?0?0 P450 ?0?0?0?0?W?n0?0?0@?-N?o?^?c?y?N,n" ?_0ua??0Qgq\xQu`0n4lN}P[0\????0?[¦¡?l?^0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Oral presentation]" "?0?0?0?0?0?0 1 !kJ0?0s0 2 !kx?S?v?N?k0??NY0?0?0?0?0?0?0 P450 n0.z?]" ?q\?T%_P[0n4lN}P[0 N?Sck*Y?0?[¦¡?l?^0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Poster presentation]" ?e,g?N?0?0?0?0?0?0?0?0?\?un0'Y??!js?0}???g CSI?^c[P[0n4lN}P[0?_q\[t?0gr¦¡?}0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Oral presentation]" ?0?0?0?0?0?0k0?0?0?0?0P450u? }??]??\_j?ik0?S|0Y0???V Qgq\xQu`0?w?\?RHYP[0?g0u?T7u0\????0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Oral presentation]" "?0?0?0?0?0?0?0?0?0?0?0P450 2C9n0 ?W?yrpu'`k0??Y0?0i?" ?OBW?O?T0Qgq\xQu`0???]ck?^0 N?Sck*Y?0n4lN}P[0?\?N?y0?\¦¡?O?N0?[¦¡?l?^0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Oral presentation]" "?0?0?0?0?0 P450 2A6 ¦¡u?Wh0hQ k d?Wz?OP[n0??$R?[?l" n4lN}P[0?\,gD0Z000\q\zfu0?o7?`0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Poster presentation]" ?b?|^y?u???0?0?0?0?0?0?bN?e,g?N?`?k0J0Q0?0@??o-N??ir?o?^n0 P?N?] "'YEN?OwBz0b0uChP[0Qgq\xQu`0?h0u?P[0-NQgim_N 0n4lN}P[0?yCQ mN0?_?vfP[0?%q\]im?S" ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Oral presentation]" ?b?|^y?u???0?0?0?0?0?0?bN?e,g?N?`?k0J0Q0?0@??o-N??ir?o?^n0 P?N?] 'YEN?OwBz0Qgq\xQu`0?h0u?P[0?h?N?l?0 P?g*Q??0?yCQ mN0?_?vfP[0q\]im?S ?e,g??f[O,{135t^O ^y8b 2015/03/25^?2015/03/28 "[Special lecture/Symposium]" ?0?0?0?0?0?00?0?0?0?0?0?0J0?0s0?0?0n0??irx?Su? };m'`n0?k? q\]im?S0 N?Sck*Y?0?[¦¡?l?^ ,{4?V?e,g?0?0?0?0?0?0xvzO'YO ?rq\ 2015/01/22^?2015/01/23 "[Oral presentation]" ?e,g?Nn0?0?0?0?0?0?0?0?0?\?un0N?Vh0j0?0?0?0?0?0+T g?0?0?0?0?0?0?0?0?03z?OP[ Ypun0?g O?q??sO0n4lN}P[0 N??0P[0?S0u?l_N?R0q\]im?S ,{68?VV??0?0?0?0?0;S?y'Yf[;Sf[Of[S??O ?]] 2014/12/11^?2014/12/12 "[Oral presentation]" ?0?0?0?0?0?0?0??dR?0O(uW0_0??g?`?n0@?-N?0?0?0?0?0?0?0?0?o?^ "q\] im?S0