薬化学研究室

昭和薬科大学研究室一覧

昭和薬科大学研究室一覧

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論文リスト（Publications 2008?）last update : 2025.11.26

2025

 

  1. Regioselectivity Inversion in the Cycloaddition Reaction between Stable Nitrile Oxides and Acylalkyne Derivatives.
    Maeda, Y.; Hashimoto, Y.; Aoki, R.; Kimura, N.; Tanaka, K. III; Tamura, O.; Morita, N.
    Chem. Pharm. Bull. 2025, 73, 1065–1074.
     

     

2024

 

  1. Gold-Catalyzed Propargylic Substitution Followed by Cycloisomerization in Ionic Liquid: Environmentally Friendly Synthesis of Polysubstituted Furans from Propargylic Alcohols and 1,3-Dicarbonyl Compounds.
    Chiaki, H.; Hashimoto, Y.; Morita, N.
    Molecules 2024, 29, 5441.
     

     

  2. Hetero Cope-Type Hydroamination of Hetero-Allenes with Oximes Having Olefin Moieties Leading to Nitrones, Causing Intramolecular Cycloaddition.
    Ide, Y.; Matsuda, N.; Osada, M.; Yamamoto, A.; Tanaka, K. III; Hashimoto, Y.; Morita, N.; Tamura, O.
    J. Org. Chem. 2024, 89, 12973–12981.
     

     

  3. Discovery of a Formal Dyotropic Rearrangement during Acid-Mediated Dioxabicyclo[4.2.1]nonanone Formation.
    Hashimoto, Y.;† Kong W.-Y.;† Tantillo, D. J. († equal contribution)
    Org. Lett. 2024, 26, 5441–5446.
     

     

  4. An Efficient Stereoselective Synthesis of cis-2,6-Disubstituted Tetrahydropyrans via Gold-Catalyzed Meyer–Schuster Rearrangement/Hydration/oxa-Michael Addition Sequence.
    Morita, N.; Yamashita, D.; Hashimoto, Y.; Tamura, O.
    Catalysts 2024, 14, 228.
     

     

  5. (E)-5-[Bromo(phenyl)methylene]-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole.
    Morita, N.; Kurami, S.; Ishii, N.; Tanaka, K. III; Hashimoto, Y.; Tamura, O.
    Molbank 2024, 2024, M1769.
     

     

  6. Gold(III)-Catalyzed Propargylic Substitution Reaction Followed by Cycloisomerization for Synthesis of Poly-Substituted Furans from N-Tosylpropargyl Amines with 1,3-Dicarbonyl Compounds.
    Morita, N.; Uchida, S.; Chiaki, H.; Ishii, N.; Tanikawa, K.; Tanaka, K. III; Hashimoto, Y.; Tamura, O.
    Molecules 2024, 29, 378.
     

     

  7. Intermolecular 1,3-Dipolar Cycloaddition Reaction of N-Carbamoyl Nitrones Generated by N-Selective Carbamoylation of Oximes with Isocyanates.
    Yamamoto, A.; Tanaka, K. III; Hashimoto, Y.; Morita, N.; Tamura, O.
    Chem. Eur. J., 2024, 30, e202303790.
    本論文はHot Paperに選出されました。
     

     

2023

 

  1. Direct Generation of N-Alkoxycarbonyl Nitrones from Oximes: Intramolecular Cycloaddition of Oximes Having Alkene Moieties.
    Sagara, H.; Suzuki, Y.; Morita, N.; Ban, S.; Tanaka, K. III; Yamamoto, A.; Hashimoto, Y.; Tamura, O.
    Adv. Synth. Catal. 2023, 365, 3927–3934.
     

     

  2. Electrophilic C3−H Alkenylation of 2,6-Dialkoxypyridine Derivatives via Pd(II)/Tl(III) Reaction System.
    Yamada, T.; Tanaka, K. III; Hashimoto, Y.; Morita, N.; Tamura, O.
    Adv. Synth. Catal. 2023, 365, 3138–3148.
    本論文はWiley社の"Hot Topic: C–H Activation"で紹介されました。
     

     

  3. Synthesis of N-Aryl Isoxazolidines by Photo-Promoted N-Selective Arylation of Oximes and Cyclization Using Hypervalent Iodine Reagents and Copper Catalyst.
    Tanaka, K. III; Yoshida, M.; Yamamoto, A.; Hashimoto, Y.; Morita, N.; Tamura, O.
    Adv. Synth. Catal. 2023, 365, 1419–1424.
     

     

  4. (Z)-5-Benzylidene-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole.
    Morita, N.; Chiaki, H.; Aonuma, S.; Tanaka, K. III; Hashimoto, Y.; Tamura, O.
    Molbank 2023, 2023, M1600.
     

     

  5. Sustainable Chemical Synthesis of 2,3-Dihydrobenzofurans/1,2,3-Trisubstituted Indanes in Water Using a Permethylated β-Cyclodextrin-tagged NHC-Gold Catalyst.
    Morita, N.; Chiaki, H.; Tanaka, K. III; Hashimoto, Y.; Tamura, O.; Krause, N.
    Synlett 2023, 34, 1425–1432.
     

     

  6. Gold-Catalyzed Formal (3+2) Cycloaddition in Ionic Liquid: Environmentally Friendly and Stereoselective Synthesis of Poly-substituted Indanes from Benzyl Alcohols with 1-Phenylpropenes.
    Morita, N.; Chiaki, H.; Ikeda, K.; Tanaka, K. III; Hashimoto, Y.; Tamura, O.
    Synlett 2023, 34, 1068–1074.
     

     

2022

 

  1. Directing-Group-Free Palladium-Catalyzed C–H Arylation of Aldoxime Using Oxime’s Umpolung Properties.
    Tanaka, K. III; Hashimoto, Y.; Morita, N.; Tamura, O.
    Org. Lett. 2022, 24, 8954–8958.
     

     

  2. Mechanism and the Origins of Periselectivity in Cycloaddition Reactions of Benzyne with Dienes.
    Hashimoto, Y.; Tantillo, D. J.
    J. Org. Chem. 2022, 87, 12954–12962.
     

     

  3. Cationic palladium(II)-catalyzed synthesis of substituted pyridines from α,β-unsaturated oxime ethers.
    Yamada, T.; Hashimoto, Y.; Tanaka, K. III; Morita, N.; Tamura, O.
    RSC Adv. 2022, 12, 21548–21557.
     

     

2021

 

  1. Enantioselective total synthesis of (+)-rubrobramide, (+)-talaramide A, and (−)-berkeleyamide D by a skeletal diversification strategy.
    Tanaka, K. III; Kobayashi, K.; Kogen, H.
    Chem. Commun. 2021, 57, 9780–9783.
     
  2. Electrophilic Epoxidation of α,β-Unsaturated Oximes with Dioxiranes and Ring Opening of the Epoxides.
    Furugoori, M.; Yoshida, K.; Hashimoto, Y.; Morita, N.; Tanaka, K. III; Tamura, O.
    Chem. Pharm. Bull. 2021, 69, 1010–1016.
     

     

  3. Gold-Catalyzed Formal [3+2] Cycloaddition of p-Quinones and 1-Phenylpropenes in Ionic Liquid: Environmentally Friendly and Stereoselective Synthesis of Benzofuran Neolignans.
    Morita, N.; Ikeda, K.; Chiaki, H.; Araki, R.; Tanaka, K. III; Hashimoto Y.; Tamura, O.
    Heterocycles 2021, 103, 714–722.
     

     

  4. Palladium(II)-Catalyzed Substituted Pyridine Synthesis from α,β-Unsaturated Oxime Ethers via a C–H Alkenylation/Aza-6π-Electrocyclization Approach.
    Yamada, T.; Hashimoto, Y.; Tanaka, K. III; Morita, N.; Tamura, O.
    Org. Lett. 2021, 23, 1659–1663.
     

     

  5. Highly Oxidized γ-Lactam-Containing Natural Products: Total Synthesis and Biological Evaluation.
    Tanaka, K. III; Kogen, H.; Kobayashi, K.
    Heterocycles 2021, 102, 1235–1285.
     

2020

 

  1. Thioether Ligand-Enabled Cationic Palladium(II)-Catalyzed Electrophilic C-H Arylation of α,β-Unsaturated Oxime Ethers.
    Yamada, T.; Hashimoto, Y.; Tanaka, K. III; Morita, N.; Tamura, O.
    J. Org. Chem. 2020, 85, 12315–12328.
     

     

  2. Synthesis and Formation Mechanism of a Compound with an Unprecedented Skeleton: Dodecahydro-4,10:5,9-diepoxydipyrrolo[3,4-b:3',4'-f][1,5]diazocine.
    Shinoda, M.; Morita, N.; Tanaka, K. III; Hashimoto, Y.; Ban, S.; Tamura, O.
    Chem. Pharm. Bull. 2020, 68, 1238–1243.
     

     

  3. Intramolecular Activation of Imidate with Cationic Gold(I) Catalyst: a New Benzylation Reaction of Alcohols
    Ban, S.; Endo, T.; Matsui, R.; Morita, N.; Hashimoto, Y.; Tanaka, K. III; Tamura, O.
    Tetrahedron Lett. 2020, 61, 152233–152235.
     

     

  4. O-Alkyl S-(Pyridin-2-yl)carbonothiolates: Operationally Simple and Highly Nitrogen-Selective Reagents for Alkoxy Carbonylation of Amino Groups.
    Suzuki, T.; Tanaka, K. III; Hashimoto, Y.; Morita, N.; Tamura, O.
    Synlett 2020